Bringing together the deeply rooted scientific expertise of Istanbul Technical University under the editorship of Prof. Dr. Hatice Ayataç, this work offers a strategic guide aligned with the United Nations Sustainable Development Goals (SDGs) and Türkiye’s development vision. Prepared with the collective contributions of expert academics from various disciplines at ITU, the book defines sustainability as an achievable goal across a broad spectrum—ranging from sustainable cities to climate action, and energy efficiency to governance and leadership. Substantiating the theoretical framework of the SDGs with contemporary approaches, regulations, and local success stories, this handbook serves as a reference source that bridges academic depth with practical application for researchers, policymakers, and private sector representatives alike.